Prenatal exposure to residential air pollution and infant mental development: modulation by antioxidants and detoxification factors.

ABSTRACT:

Background

Air pollution effects on children's neurodevelopment have recently been suggested to occur most likely through the oxidative stress pathway.

Objective

We aimed to assess whether prenatal exposure to residential air pollution is associated with impaired infant mental development, and whether antioxidant/detoxification factors modulate this association.

Methods

In the Spanish INfancia y Medio Ambiente (INMA; Environment and Childhood) Project, 2,644 pregnant women were recruited during their first trimester. Nitrogen dioxide (NO2) and benzene were measured with passive samplers covering the study areas. Land use regression models were developed for each pollutant to predict average outdoor air pollution levels for the entire pregnancy at each residential addr

SUBMITTER: Guxens M 

PROVIDER: S-EPMC3261939 | biostudies-literature | 2012 Jan

REPOSITORIES: biostudies-literature