Photo-cross-linkers incorporated into G-protein-coupled receptors in mammalian cells: a ligand comparison.

ABSTRACT: Capturing the right ligand at the right spot: a well-balanced system for non-natural amino acid mutagenesis allows the ligand binding sites of a class II G-protein coupled receptor to be mapped and distinct binding domains to be identified for different ligands in the native environment of mammalian cells.

SUBMITTER: Coin I 

PROVIDER: S-EPMC3262126 | biostudies-literature | 2011 Aug

REPOSITORIES: biostudies-literature