Incidence of acquired CNS demyelinating syndromes in a multiethnic cohort of children.

ABSTRACT:

Objective

To determine whether the incidence and clinical features of pediatric multiple sclerosis (MS) and other forms of pediatric acquired demyelinating syndromes (ADS) vary by race/ethnicity in a population-based cohort.

Methods

We used a combination of electronic database searches followed by complete medical records review to identify all children diagnosed with MS and ADS in the multiethnic membership of Kaiser Permanente Southern California from January 1, 2004, to December 31, 2009. Incidence rates were standardized to the US census by age and gender.

Results

We identified 81 incident cases of ADS from 4.87 million person-years of observation in children 0-18 years of age. The incidence rate of pediatric MS was 0.51 per 100,000 person-years (95% confidence in

SUBMITTER: Langer-Gould A 

PROVIDER: S-EPMC3265045 | biostudies-literature | 2011 Sep

REPOSITORIES: biostudies-literature