Genetic architecture of gene expression in ovine skeletal muscle.

ABSTRACT:

Background

In livestock populations the genetic contribution to muscling is intensively monitored in the progeny of industry sires and used as a tool in selective breeding programs. The genes and pathways conferring this genetic merit are largely undefined. Genetic variation within a population has potential, amongst other mechanisms, to alter gene expression via cis- or trans-acting mechanisms in a manner that impacts the functional activities of specific pathways that contribute to muscling traits. By integrating sire-based genetic merit information for a muscling trait with progeny-based gene expression data we directly tested the hypothesis that there is genetic structure in the gene expression program in ovine skeletal muscle.

Results

The genetic performance of six sire

SUBMITTER: Kogelman LJ 

PROVIDER: S-EPMC3265547 | biostudies-literature | 2011 Dec

REPOSITORIES: biostudies-literature