Pharmacogenetics of antipsychotic treatment response and side effects.

ABSTRACT: Antipsychotic drugs are particularly interesting in pharmacogenetic studies as they are associated with a large interindividual variability in terms of response and side effects and, therefore, frequently need to be discontinued, requiring switches to other antipsychotics. Any information that allows the prediction of outcome to a given antipsychotic in a particular patient will, therefore, be of great help for the clinician to minimize time and find the right drug for the right patient, thus optimizing response and minimizing side effects. This will also have a substantial impact on compliance and doctor-patient relationships. Moreover, antipsychotic drug treatments are often required for life-long treatment and are also frequently prescribed to the more 'vulnerable' populations: children

SUBMITTER: Mackenzie B 

PROVIDER: S-EPMC3266305 | biostudies-literature | 2010 Mar

REPOSITORIES: biostudies-literature