Objective vs. subjective measurements of sleep in depressed insomniacs: first night effect or reverse first night effect?

ABSTRACT:

Study objectives

This study examined changes in sleep parameters between the laboratory and the home setting before and after laboratory monitoring in depressed insomniacs undergoing treatment.

Methods

This study was a post hoc analysis of a double-blind, randomized, placebo-controlled clinical trial performed with 60 depressed, insomniac outpatients. Patients underwent actigraphic monitoring along with sleep diaries over a continuous 2-week period. After one week of baseline monitoring, subjects spent one night in the laboratory with concurrent actigraphic and PSG monitoring with sleep diaries. Actigraphic monitoring and sleep diaries were continued for another week at home, along with initiation of open-label fluoxetine (FLX).

Results

Actigraphically recorded labora

SUBMITTER: McCall C 

PROVIDER: S-EPMC3266334 | biostudies-literature | 2012 Feb

REPOSITORIES: biostudies-literature