Randomized, double-blind clinical trial of two different modes of positive airway pressure therapy on adherence and efficacy in children.

ABSTRACT:

Study objectives

To determine the effects of bilevel positive airway pressure with pressure release technology (Bi-Flex) on adherence and efficacy in children and adolescents compared to standard continuous positive airway pressure (CPAP) therapy. We hypothesized that Bi-Flex would result in improved adherence but similar efficacy to CPAP.

Methods

This was a randomized, double-blinded clinical trial. Patients with obstructive sleep apnea were randomized to CPAP or Bi-Flex. Repeat polysomnography was performed on pressure at 3 months. Objective adherence data were obtained at 1 and 3 months.

Results

56 children and adolescents were evaluated. There were no significant differences in the number of nights the device was turned on, or the mean number of minutes used at pr

SUBMITTER: Marcus CL 

PROVIDER: S-EPMC3266335 | biostudies-literature | 2012 Feb

REPOSITORIES: biostudies-literature