Pulmonary Nodules: growth rate assessment in patients by using serial CT and three-dimensional volumetry.

ABSTRACT:

Purpose

To determine the precision of a three-dimensional (3D) method for measuring the growth rate of solid and subsolid nodules and its ability to detect abnormal growth rates.

Materials and methods

This study was approved by the Institutional Research Board and was HIPAA compliant. Informed consent was waived. The growth rates of 123 lung nodules in 59 patients who had undergone lung cancer screening computed tomography (CT) were measured by using a 3D semiautomated computer-assisted volume method. Clinical stability was established with long-term CT follow-up (mean, 6.4 years±1.9 [standard deviation]; range, 2.0-8.5 years). A mean of 4.1 CT examinations per patient±1.2 (range, two to seven CT examinations per patient) was analyzed during 2.4 years±0.5 after baseline CT.

SUBMITTER: Ko JP 

PROVIDER: S-EPMC3267080 | biostudies-literature | 2012 Feb

REPOSITORIES: biostudies-literature