Chronic hyperglycemia and subclinical myocardial injury.

ABSTRACT:

Objectives

The purpose of this study was to examine the association between hyperglycemia and subclinical myocardial injury in persons without clinically evident coronary heart disease (CHD).

Background

Hyperglycemia is associated with an increased risk of cardiac events, but limited information is available on its relationship to subclinical myocardial damage. Elevated cardiac troponin T even below traditional detection levels can be detected by a novel high-sensitivity assay.

Methods

We examined the association between baseline glycated hemoglobin (HbA1c) and high-sensitivity cardiac troponin T (hs-cTnT) in 9,661 participants free of CHD and heart failure in the ARIC (Atherosclerosis Risk in Communities) study. Multivariable logistic regression models characterized

SUBMITTER: Rubin J 

PROVIDER: S-EPMC3267958 | biostudies-literature | 2012 Jan

REPOSITORIES: biostudies-literature