A Parallel Study of mRNA and microRNA Profiling of Peripheral Blood in Young Adult Women.

ABSTRACT:

Background

Aging is a complex process that involves the interplay of genetic, epigenetic, and environmental factors. Identifying aging-related biomarkers holds great potential for improving our understanding of complex physiological changes, thereby providing a means to investigate the mechanism by which aging influences various diseases.

Method and results

We performed a parallel study of microRNA and gene expression profiling of peripheral blood in a group of healthy young adult women, among which 13 were aged 22-25 and 9 were aged 36-39 years old. We identified a significantly distinct pattern of microRNA, but not gene expression profiling, between these two young adult women groups. We also performed correlation analysis of expression levels between all pairs of age-asso

SUBMITTER: Sredni ST 

PROVIDER: S-EPMC3268602 | biostudies-literature | 2011

REPOSITORIES: biostudies-literature