Predicting survival in frontotemporal dementia with motor neuron disease.

ABSTRACT:

Objective

To determine whether clinical and demographic features are associated with prognosis in patients with frontotemporal dementia and motor neuron disease (FTD-MND).

Methods

This was a case series of FTD-MND categorized according to behavioral- or language-dominant symptoms at presentation and throughout the disease course. Demographic, clinical, imaging, and survival data were analyzed with respect to dominant FTD-MND type. Voxel-based morphometry was used to assess and compare regional patterns of atrophy in behavioral- and language-dominant FTD-MND types.

Results

Of the 56 patients with FTD-MND who were identified, 31 had dominant behavioral symptoms and 25 had dominant language symptoms; 53 patients had died. A survival difference was present between types,

SUBMITTER: Coon EA 

PROVIDER: S-EPMC3269075 | biostudies-literature | 2011 May

REPOSITORIES: biostudies-literature