Psychopathic tendencies and mesolimbic recruitment by cues for instrumental and passively obtained rewards.

ABSTRACT: Psychopathy is a constellation of self-serving attitudes and antisocial behaviors with little regard to cost to self and others. Might this symptomatology arise in part from an exaggerated response of brain motivational circuitry to prospective rewards? We examined whether psychopathic tendencies are associated with increased recruitment of incentive neurocircuitry during anticipation of instrumental and conditioned rewards. Healthy controls completed the Psychopathic Personality Inventory (PPI), then were presented with response-contingent and passively delivered rewards during functional MRI. PPI scores correlated negatively with reaction time to incentivized targets, but not with reaction time to non-incentivized targets. PPI scores also correlated positively with recruitment of ventral

SUBMITTER: Bjork JM 

PROVIDER: S-EPMC3269887 | biostudies-literature | 2012 Feb

REPOSITORIES: biostudies-literature