Mining the Gene Wiki for functional genomic knowledge.

ABSTRACT:

Background

Ontology-based gene annotations are important tools for organizing and analyzing genome-scale biological data. Collecting these annotations is a valuable but costly endeavor. The Gene Wiki makes use of Wikipedia as a low-cost, mass-collaborative platform for assembling text-based gene annotations. The Gene Wiki is comprised of more than 10,000 review articles, each describing one human gene. The goal of this study is to define and assess a computational strategy for translating the text of Gene Wiki articles into ontology-based gene annotations. We specifically explore the generation of structured annotations using the Gene Ontology and the Human Disease Ontology.

Results

Our system produced 2,983 candidate gene annotations using the Disease Ontology and 11,022 ca

SUBMITTER: Good BM 

PROVIDER: S-EPMC3271090 | biostudies-literature | 2011 Dec

REPOSITORIES: biostudies-literature