Efficacy and safety of enoxaparin versus unfractionated heparin during percutaneous coronary intervention: systematic review and meta-analysis.

ABSTRACT:

Objective

To determine the efficacy and safety of enoxaparin compared with unfractionated heparin during percutaneous coronary intervention.

Design

Systematic review and meta-analysis.

Data sources

Medline and Cochrane database of systematic reviews, January 1996 to May 2011.

Study selection

Randomised and non-randomised studies comparing enoxaparin with unfractionated heparin during percutaneous coronary intervention and reporting on both mortality (efficacy end point) and major bleeding (safety end point) outcomes.

Data extraction

Sample size, characteristics, and outcomes, extracted independently and analysed.

Data synthesis

23 trials representing 30,966 patients were identified, including 10,243 patients (33.1%) undergoing primary percutaneous

SUBMITTER: Silvain J 

PROVIDER: S-EPMC3271999 | biostudies-literature | 2012 Feb

REPOSITORIES: biostudies-literature