A concise total synthesis of (±)- and (-)-okilactomycin D.

ABSTRACT: The spirotetronate okilactomycin D (7) has been efficiently synthesized by a route featuring a substrate-controlled, diastereoselective (8:1) intramolecular Diels-Alder (IMDA) reaction of 11. The assigned absolute configuration of (-)-7 was confirmed.

SUBMITTER: Niu D 

PROVIDER: S-EPMC3272355 | biostudies-literature | 2012 Feb

REPOSITORIES: biostudies-literature