Intravenous vitamin C administration reduces fatigue in office workers: a double-blind randomized controlled trial.

ABSTRACT:

Background

Studies of the efficacy of vitamin C treatment for fatigue have yielded inconsistent results. One of the reasons for this inconsistency could be the difference in delivery routes. Therefore, we planned a clinical trial with intravenous vitamin C administration.

Methods

We evaluated the effect of intravenous vitamin C on fatigue in office workers. A group of 141 healthy volunteers, aged 20 to 49 years participated in this randomized, double-blind, controlled clinical trial. The trial group received 10 grams of vitamin C with normal saline intravenously, while the placebo group received normal saline only. Since vitamin C is a well-known antioxidant, oxidative stress was measured. Fatigue score, oxidative stress, and plasma vitamin C levels were measured before inte

SUBMITTER: Suh SY 

PROVIDER: S-EPMC3273429 | biostudies-literature | 2012 Jan

REPOSITORIES: biostudies-literature