Genome-wide transcriptional profiling of appressorium development by the rice blast fungus Magnaporthe oryzae.

ABSTRACT: The rice blast fungus Magnaporthe oryzae is one of the most significant pathogens affecting global food security. To cause rice blast disease the fungus elaborates a specialised infection structure called an appressorium. Here, we report genome wide transcriptional profile analysis of appressorium development using next generation sequencing (NGS). We performed both RNA-Seq and High-Throughput SuperSAGE analysis to compare the utility of these procedures for identifying differential gene expression in M. oryzae. We then analysed global patterns of gene expression during appressorium development. We show evidence for large-scale gene expression changes, highlighting the role of autophagy, lipid metabolism and melanin biosynthesis in appressorium differentiation. We reveal the role of the Pm

SUBMITTER: Soanes DM 

PROVIDER: S-EPMC3276559 | biostudies-literature | 2012 Feb

REPOSITORIES: biostudies-literature