Hepcidin: A useful marker in chronic obstructive pulmonary disease.

ABSTRACT:

Purpose

This study was designed to evaluate the levels of hepcidin in the serum of patients with chronic obstructive pulmonary disease (COPD).

Methods

In the study, 74 male patients (ages 45-75) in a stable period for COPD were grouped as Group I: Mild COPD (n:25), Group II: Moderate COPD (n:24), and Group III: Severe COPD (n:25). Healthy non-smoker males were included in Group IV (n:35) as a control group. The differences of hepcidin level among all the groups were examined. Also, in the patient groups with COPD, hepcidin level was compared with age, body mass index, cigarette (package/year), blood parameters (iron, total iron binding capacity, ferritin, hemoglobin, hematocrit [hct]), respiratory function tests, and arterial blood gas results.

Results

Although there

SUBMITTER: Duru S 

PROVIDER: S-EPMC3277039 | biostudies-literature | 2012 Jan

REPOSITORIES: biostudies-literature