Analysis of human fibroadenomas using three-dimensional impedance maps.

ABSTRACT: Three-dimensional impedance maps (3DZMs) are virtual volumes of acoustic impedance values constructed from histology to represent tissue microstructure acoustically. From the 3DZM, the ultrasonic backscattered power spectrum can be predicted and model based scatterer properties, such as effective scatterer diameter (ESD), can be estimated. Additionally, the 3DZM can be exploited to visualize and identify possible scattering sites, which may aid in the development of more effective scattering models to better represent the ultrasonic interaction with underlying tissue microstructure. In this study, 3DZMs were created from a set of human fibroadenoma samples. ESD estimates were made assuming a fluid-filled sphere form factor model from 3DZMs of volume 300×300×300 μm. For a collection of 33 i

SUBMITTER: Dapore AJ 

PROVIDER: S-EPMC3277289 | biostudies-literature | 2011 Jun

REPOSITORIES: biostudies-literature