Proteome adaptation to high temperatures in the ectothermic hydrothermal vent Pompeii worm.

ABSTRACT: Taking advantage of the massive genome sequencing effort made on thermophilic prokaryotes, thermal adaptation has been extensively studied by analysing amino acid replacements and codon usage in these unicellular organisms. In most cases, adaptation to thermophily is associated with greater residue hydrophobicity and more charged residues. Both of these characteristics are positively correlated with the optimal growth temperature of prokaryotes. In contrast, little information has been collected on the molecular 'adaptive' strategy of thermophilic eukaryotes. The Pompeii worm A. pompejana, whose transcriptome has recently been sequenced, is currently considered as the most thermotolerant eukaryote on Earth, withstanding the greatest thermal and chemical ranges known. We investigated the am

SUBMITTER: Jollivet D 

PROVIDER: S-EPMC3277501 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature