High-affinity fluorescent ligands for the 5-HT(3) receptor.

ABSTRACT: The synthesis, photophysical and biological characterization of a small library of fluorescent 5-HT(3) receptor ligands is described. Several of these novel granisetron conjugates have high quantum yields and show high affinity for the human 5-HT(3)AR.

SUBMITTER: Simonin J 

PROVIDER: S-EPMC3277886 | biostudies-literature | 2012 Jan

REPOSITORIES: biostudies-literature