Genetic variation in odorant receptors contributes to variation in olfactory behavior in a natural population of Drosophila melanogaster.

ABSTRACT: Chemoreception is a principle modality by which organisms gain information from their environment, and extensive variation in odor-mediated behavior has been documented within and among species. To examine the mechanisms by which sensory systems mediate these responses, we ask to what extent variation in Drosophila melanogaster odorant receptor genes contributes to variation in odor-mediated behavior. Significant differences in behavioral responses to structurally similar odorants, methyl hexanoate and ethyl hexanoate, were found in a natural population. Polymorphisms in 3 genomic regions (Or22a/Or22b, Or35a, and Or47a) were identified and associated with variation in behavior to these esters. Overall similarity in association profiles for both odorants was observed, except for Or47a in wh

SUBMITTER: Richgels PK 

PROVIDER: S-EPMC3278676 | biostudies-literature | 2012 Mar

REPOSITORIES: biostudies-literature