A comparison study on feature selection of DNA structural properties for promoter prediction.

ABSTRACT:

Background

Promoter prediction is an integrant step for understanding gene regulation and annotating genomes. Traditional promoter analysis is mainly based on sequence compositional features. Recently, many kinds of structural features have been employed in promoter prediction. However, considering the high-dimensionality and overfitting problems, it is unfeasible to utilize all available features for promoter prediction. Thus it is necessary to choose some appropriate features for the prediction task.

Results

This paper conducts an extensive comparison study on feature selection of DNA structural properties for promoter prediction. Firstly, to examine whether promoters possess some special structures, we carry out a systematical comparison among the profiles of thirteen str

SUBMITTER: Gan Y 

PROVIDER: S-EPMC3280155 | biostudies-literature | 2012 Jan

REPOSITORIES: biostudies-literature