Vaccination against 2009 pandemic H1N1 in a population dynamical model of Vancouver, Canada: timing is everything.

ABSTRACT:

Background

Much remains unknown about the effect of timing and prioritization of vaccination against pandemic (pH1N1) 2009 virus on health outcomes. We adapted a city-level contact network model to study different campaigns on influenza morbidity and mortality.

Methods

We modeled different distribution strategies initiated between July and November 2009 using a compartmental epidemic model that includes age structure and transmission network dynamics. The model represents the Greater Vancouver Regional District, a major North American city and surrounding suburbs with a population of 2 million, and is parameterized using data from the British Columbia Ministry of Health, published studies, and expert opinion. Outcomes are expressed as the number of infections and deaths aver

SUBMITTER: Conway JM 

PROVIDER: S-EPMC3280345 | biostudies-literature | 2011 Dec

REPOSITORIES: biostudies-literature