Effect of Lactobacillus salivarius bacteriocin Abp118 on the mouse and pig intestinal microbiota.

ABSTRACT: Lactobacilli are gram-positive bacteria that are a subdominant element in the human gastrointestinal microbiota, and which are commonly used in the food industry. Some lactobacilli are considered probiotic, and have been associated with health benefits. However, there is very little culture-independent information on how consumed probiotic microorganisms might affect the entire intestinal microbiota. We therefore studied the impact of the administration of Lactobacillus salivarius UCC118, a microorganism well characterized for its probiotic properties, on the composition of the intestinal microbiota in two model animals. UCC118 has anti-infective activity due to production of the bacteriocin Abp118, a broad-spectrum class IIb bacteriocin, which we hypothesized could impact the microbiota.

SUBMITTER: Riboulet-Bisson E 

PROVIDER: S-EPMC3281923 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature