Nocturnal temperature controlled laminar airflow for treating atopic asthma: a randomised controlled trial.

ABSTRACT:

Objective

To determine whether environmental control using nocturnal temperature controlled laminar airflow (TLA) treatment could improve the quality of life of patients with persistent atopic asthma.

Design

Randomised, double-blind, placebo-controlled, parallel-group trial. Setting Nineteen European asthma clinics.

Participants

312 patients aged 7-70 with inadequately controlled persistent atopic asthma.

Main outcome measure

Proportion of patients with an increase of ≥0.5 points in asthma quality of life score after 1 year of treatment.

Results

TLA devices were successfully installed in the bedrooms of 282 (90%) patients included in the primary efficacy analysis. There was a difference in treatment response rate between active (143 of 189, 76%) and plac

SUBMITTER: Boyle RJ 

PROVIDER: S-EPMC3282042 | biostudies-literature | 2012 Mar

REPOSITORIES: biostudies-literature