A method for computing an inventory of metazoan mitochondrial gene order rearrangements.

ABSTRACT:

Background

Changes in the order of mitochondrial genes are a good source of information for phylogenetic investigations. Phylogenetic hypotheses are often supported by parsimonious mitochondrial gene order rearrangement scenarios. CREx is a heuristic for computing short pairwise rearrangement scenarios for metazoan mitochondrial gene orders. Different from other methods, CREx considers four types of rearrangement operations: inversions, transpositions, inverse transpositions, and tandem duplication random loss operations.

Results

An extensive analysis of the CREx reconstructions for artificial data has been presented and it is shown how the quality of the reconstructed rearrangement scenarios depends on the type of rearrangement model and additional parameter values. Moreove

SUBMITTER: Bernt M 

PROVIDER: S-EPMC3283314 | biostudies-literature | 2011 Oct

REPOSITORIES: biostudies-literature