Major lipids, apolipoproteins, and risk of vascular disease.

ABSTRACT:

Context

Associations of major lipids and apolipoproteins with the risk of vascular disease have not been reliably quantified.

Objective

To assess major lipids and apolipoproteins in vascular risk.

Design, setting, and participants

Individual records were supplied on 302,430 people without initial vascular disease from 68 long-term prospective studies, mostly in Europe and North America. During 2.79 million person-years of follow-up, there were 8857 nonfatal myocardial infarctions, 3928 coronary heart disease [CHD] deaths, 2534 ischemic strokes, 513 hemorrhagic strokes, and 2536 unclassified strokes.

Main outcome measures

Hazard ratios (HRs), adjusted for several conventional factors, were calculated for 1-SD higher values: 0.52 log(e) triglyceride, 15 mg/dL hig

SUBMITTER: Emerging Risk Factors Collaboration 

PROVIDER: S-EPMC3284229 | biostudies-literature | 2009 Nov

REPOSITORIES: biostudies-literature