The HIV-1 epidemic in Bolivia is dominated by subtype B and CRF12_BF "family" strains.

ABSTRACT:

Background

Molecular epidemiological studies of HIV-1 in South America have revealed the occurrence of subtypes B, F1 and BF1 recombinants. Even so, little information concerning the HIV-1 molecular epidemiology in Bolivia is available. In this study we performed phylogenetic analyses from samples collected in Bolivia at two different points in time over a 10 year span. We analyzed these samples to estimate the trends in the HIV subtype and recombinant forms over time.

Materials and methods

Fifty one HIV-1 positive samples were collected in Bolivia over two distinct periods (1996 and 2005). These samples were genetically characterized based on partial pol protease/reverse transcriptase (pr/rt) and env regions. Alignment and neighbor-joining (NJ) phylogenetic analyses were es

SUBMITTER: Guimaraes ML 

PROVIDER: S-EPMC3285048 | biostudies-literature | 2012 Jan

REPOSITORIES: biostudies-literature