Unknown

Dataset Information

0

Identification of cancer cell-line origins using fluorescence image-based phenomic screening.

ABSTRACT: Universal phenotyping techniques that can discriminate among various states of biological systems have great potential. We applied 557 fluorescent library compounds to NCI's 60 human cancer cell-lines (NCI-60) to generate a systematic fluorescence phenotypic profiling data. By the kinetic fluorescence intensity analysis, we successfully discriminated the organ origin of all the 60 cell-lines.

SUBMITTER: Lee JS 

PROVIDER: S-EPMC3285665 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature

Json Xml
altmetric image

Publications

Identification of cancer cell-line origins using fluorescence image-based phenomic screening.

Lee Jun-Seok JS   Kim Yun Kyung YK   Kim Han Jo HJ   Hajar Siti S   Tan Yee Ling YL   Kang Nam-Young NY   Ng Shin Hui SH   Yoon Chang No CN   Chang Young-Tae YT  

PloS one 20120223 2

Universal phenotyping techniques that can discriminate among various states of biological systems have great potential. We applied 557 fluorescent library compounds to NCI's 60 human cancer cell-lines (NCI-60) to generate a systematic fluorescence phenotypic profiling data. By the kinetic fluorescence intensity analysis, we successfully discriminated the organ origin of all the 60 cell-lines. ...[more]