Genomic organisation of the Mal d 1 gene cluster on linkage group 16 in apple.

ABSTRACT: European populations exhibit progressive sensitisation to food allergens, and apples are one of the foods for which sensitisation is observed most frequently. Apple cultivars vary greatly in their allergenic characteristics, and a better understanding of the genetic basis of low allergenicity may therefore allow allergic individuals to increase their fruit intake. Mal d 1 is considered to be a major apple allergen, and this protein is encoded by the most complex allergen gene family. Not all Mal d 1 members are likely to be involved in allergenicity. Therefore, additional knowledge about the existence and characteristics of the different Mal d 1 genes is required. In the present study, we investigated the genomic organisation of the Mal d 1 gene cluster in linkage group 16 of apple through

SUBMITTER: Pagliarani G 

PROVIDER: S-EPMC3285766 | biostudies-literature | 2012 Mar

REPOSITORIES: biostudies-literature