Accelerated evolution and coevolution drove the evolutionary history of AGPase sub-units during angiosperm radiation.

ABSTRACT:

Background and aims

ADP-glucose pyrophosphorylase (AGPase) is a key enzyme of starch biosynthesis. In the green plant lineage, it is composed of two large (LSU) and two small (SSU) sub-units encoded by paralogous genes, as a consequence of several rounds of duplication. First, our aim was to detect specific patterns of molecular evolution following duplication events and the divergence between monocotyledons and dicotyledons. Secondly, we investigated coevolution between amino acids both within and between sub-units.

Methods

A phylogeny of each AGPase sub-unit was built using all gymnosperm and angiosperm sequences available in databases. Accelerated evolution along specific branches was tested using the ratio of the non-synonymous to the synonymous substitution rate. Coevol

SUBMITTER: Corbi J 

PROVIDER: S-EPMC3286274 | biostudies-literature | 2012 Mar

REPOSITORIES: biostudies-literature