FMRI reactivity to high-calorie food pictures predicts short- and long-term outcome in a weight-loss program.

ABSTRACT: Behavioral studies have suggested that food cues have stronger motivating effects in obese than in normal-weight individuals, which may be a risk factor underlying obesity. Previous cross-sectional neuroimaging studies have suggested that this difference is mediated by increased reactivity to food cues in parts of the reward system in obese individuals. To date, however, only a few prospective neuroimaging studies have been conducted to examine whether individual differences in brain activation elicited by food cues can predict differences in weight change. We used functional magnetic resonance imaging (fMRI) to investigate activation in reward-system as well as other brain regions in response to viewing high-calorie food vs. control pictures in 25 obese individuals before and after a 12-w

SUBMITTER: Murdaugh DL 

PROVIDER: S-EPMC3287079 | biostudies-literature | 2012 Feb

REPOSITORIES: biostudies-literature