Lactase non-persistent genotype influences milk consumption and gastrointestinal symptoms in Northern Russians.

ABSTRACT:

Background

Milk is an important source of nutrients. The consumption of milk, however, may cause abdominal complaints in lactose intolerant individuals. The frequency of -13910C/C genotype is known to be high among Northern Russians, exceeding the prevalence in northern Europe. In our study we tested two hypotheses: 1) subjects with lactase non-persistent genotype (-13910C/C) have more gastrointestinal (GI) symptoms associated with milk 2) subjects with lactase non-persistence avoid using milk.

Methods

In total, 518 students aged 17 to 26 years were randomly selected from different departments in the Northern State Medical University (NSMU) for genotyping the lactase activity-defining -13910C/T variant. All subjects filled in a questionnaire covering their personal data, sel

SUBMITTER: Khabarova Y 

PROVIDER: S-EPMC3287141 | biostudies-literature | 2011 Nov

REPOSITORIES: biostudies-literature