AlgaGEM--a genome-scale metabolic reconstruction of algae based on the Chlamydomonas reinhardtii genome.

ABSTRACT:

Background

Microalgae have the potential to deliver biofuels without the associated competition for land resources. In order to realise the rates and titres necessary for commercial production, however, system-level metabolic engineering will be required. Genome scale metabolic reconstructions have revolutionized microbial metabolic engineering and are used routinely for in silico analysis and design. While genome scale metabolic reconstructions have been developed for many prokaryotes and model eukaryotes, the application to less well characterized eukaryotes such as algae is challenging not at least due to a lack of compartmentalization data.

Results

We have developed a genome-scale metabolic network model (named AlgaGEM) covering the metabolism for a compartmentalized alg

SUBMITTER: Dal'Molin CG 

PROVIDER: S-EPMC3287588 | biostudies-literature | 2011 Dec

REPOSITORIES: biostudies-literature