Ontology highlight
ABSTRACT:
SUBMITTER: Shen YC
PROVIDER: S-EPMC3288529 | biostudies-literature | 2012 Mar
REPOSITORIES: biostudies-literature
Developmental biology 20111222 1
Macrophage migration inhibitory factor (MIF) plays versatile roles in the immune system. MIF is also widely expressed during embryonic development, particularly in the nervous system, although its roles in neural development are only beginning to be understood. Evidence from frogs, mice and zebrafish suggests that MIF has a major role as a neurotrophin in the early development of sensory systems, including the auditory system. Here we show that the zebrafish mif pathway is required for both sens ...[more]