Retinal vessel caliber among people with acquired immunodeficiency syndrome: relationships with disease-associated factors and mortality.

ABSTRACT:

Purpose

To evaluate relationships between retinal vessel caliber, AIDS-related factors, and mortality.

Design

Longitudinal, observational cohort study.

Methods

We evaluated data for participants without ocular opportunistic infections at initial examination (baseline) in the Longitudinal Studies of the Ocular Complications of AIDS (1998-2008). Semi-automated evaluation of fundus photographs (1 eye/participant) determined central retinal artery equivalent (CRAE), central retinal vein equivalent (CRVE), and arteriole-to-venule ratio (AVR) at baseline. Multiple linear regression models, using forward selection, identified independent relationships between indices and various host- and disease-related variables.

Results

Included were 1250 participants. Mean follow-

SUBMITTER: Gangaputra S 

PROVIDER: S-EPMC3289046 | biostudies-literature | 2012 Mar

REPOSITORIES: biostudies-literature