Effect of diet composition on energy expenditure during weight loss: the POUNDS LOST Study.

ABSTRACT:

Background

Weight loss reduces energy expenditure, but the contribution of different macronutrients to this change is unclear.

Hypothesis

We tested the hypothesis that macronutrient composition of the diet might affect the partitioning of energy expenditure during weight loss.

Design

A substudy of 99 participants from the Preventing Overweight Using Novel Dietary Strategies (POUNDS LOST) trial had total energy expenditure (TEE) measured by doubly labeled water, and resting energy expenditure (REE) measured by indirect calorimetry at baseline and repeated at 6 months in 89 participants. Participants were randomly assigned to one of four diets with either 15 or 25% protein and 20 or 40% fat.

Results

TEE and REE were positively correlated with each other and with

SUBMITTER: Bray GA 

PROVIDER: S-EPMC3289771 | biostudies-literature | 2012 Mar

REPOSITORIES: biostudies-literature