Myocardial viability and survival in ischemic left ventricular dysfunction.

ABSTRACT:

Background

The assessment of myocardial viability has been used to identify patients with coronary artery disease and left ventricular dysfunction in whom coronary-artery bypass grafting (CABG) will provide a survival benefit. However, the efficacy of this approach is uncertain.

Methods

In a substudy of patients with coronary artery disease and left ventricular dysfunction who were enrolled in a randomized trial of medical therapy with or without CABG, we used single-photon-emission computed tomography (SPECT), dobutamine echocardiography, or both to assess myocardial viability on the basis of prespecified thresholds.

Results

Among the 1212 patients enrolled in the randomized trial, 601 underwent assessment of myocardial viability. Of these patients, we randomly assig

SUBMITTER: Bonow RO 

PROVIDER: S-EPMC3290901 | biostudies-literature | 2011 Apr

REPOSITORIES: biostudies-literature