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The non-LTR retrotransposons in Ciona intestinalis: new insights into the evolution of chordate genomes.


ABSTRACT:

Background

Non-long terminal repeat (non-LTR) retrotransposons have contributed to shaping the structure and function of genomes. In silico and experimental approaches have been used to identify the non-LTR elements of the urochordate Ciona intestinalis. Knowledge of the types and abundance of non-LTR elements in urochordates is a key step in understanding their contribution to the structure and function of vertebrate genomes.

Results

Consensus elements phylogenetically related to the I, LINE1, LINE2, LOA and R2 elements of the 14 eukaryotic non-LTR clades are described from C. intestinalis. The ascidian elements showed conservation of both the reverse transcriptase coding sequence and the overall structural organization seen in each clade. The apurinic/apyrimidinic endonucl

SUBMITTER: Permanyer J 

PROVIDER: S-EPMC329123 | biostudies-literature | 2003

REPOSITORIES: biostudies-literature