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Novel parvovirus and related variant in human plasma.


ABSTRACT: We report a novel parvovirus (PARV4) and related variants in pooled human plasma used in the manufacture of plasma-derived medical products. Viral DNA was detected by using highly selective polymerase chain reaction assays; 5% of pools tested positive, and amounts of DNA ranged from <500 copies/mL to >106 copies/mL plasma.

SUBMITTER: Fryer JF 

PROVIDER: S-EPMC3291395 | biostudies-literature | 2006 Jan

REPOSITORIES: biostudies-literature

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Novel parvovirus and related variant in human plasma.

Fryer Jacqueline F JF   Kapoor Amit A   Minor Philip D PD   Delwart Eric E   Baylis Sally A SA  

Emerging infectious diseases 20060101 1


We report a novel parvovirus (PARV4) and related variants in pooled human plasma used in the manufacture of plasma-derived medical products. Viral DNA was detected by using highly selective polymerase chain reaction assays; 5% of pools tested positive, and amounts of DNA ranged from <500 copies/mL to >106 copies/mL plasma. ...[more]

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