Molecular analysis of fluoroquinolone-resistant Salmonella Paratyphi A isolate, India.

ABSTRACT: Salmonella enterica serovar Paratyphi A is increasingly a cause of enteric fever. Sequence analysis of an Indian isolate showed a unique strain with high-level resistance to ciprofloxacin associated with double mutations in the DNA gyrase subunit gyrA (Ser83-->Phe and Asp87-->Gly) and a mutation in topoisomerase IV subunit parC (Ser80-->Arg).

SUBMITTER: Nair S 

PROVIDER: S-EPMC3291429 | biostudies-literature | 2006 Mar

REPOSITORIES: biostudies-literature