Local epidemic history as a predictor of tuberculosis incidence in Saskatchewan Aboriginal communities.

ABSTRACT:

Background

Average tuberculosis (TB) incidence rates are high in Canadian Aboriginal communities, but there is significant variability within this group.

Objective

To determine whether local history of post-contact TB epidemics is predictive of contemporary epidemiology among Aboriginal communities in Saskatchewan, Canada.

Methods

TB incidence, age-specific morbidity patterns and rates of clustering of TB genotypes from 1986 to 2004 were compared between two groups of communities: Group 1, in which post-contact epidemics of TB were established around 1870, and Group 2, in which they were delayed until after 1920. Concomitant effects of socio-economic and geographic variables were explored with multivariate models.

Results

Group 2 communities were characterized

SUBMITTER: Pepperell C 

PROVIDER: S-EPMC3292043 | biostudies-literature | 2011 Jul

REPOSITORIES: biostudies-literature