Genotyping of 73 UM-SCC head and neck squamous cell carcinoma cell lines.

ABSTRACT:

Background

We established multiple University of Michigan Squamous Cell Carcinoma (UM-SCC) cell lines. With time, these have been distributed to other labs all over the world. Recent scientific discussions have noted the need to confirm the origin and identity of cell lines in grant proposals and journal articles. We genotyped the UM-SCC cell lines in our collection to confirm their unique identity.

Method

Early-passage UM-SCC cell lines were genotyped and photographed.

Results

Thus far, 73 unique head and neck UM-SCC cell lines (from 65 donors, including 21 lines from 17 females) were genotyped. In 7 cases, separate cell lines were established from the same donor.

Conclusions

These results will be posted on the UM Head and Neck SPORE Tissue Core website for ot

SUBMITTER: Brenner JC 

PROVIDER: S-EPMC3292176 | biostudies-literature | 2010 Apr

REPOSITORIES: biostudies-literature