Severe lactic acidosis and acute renal failure following ingestion of metformin and kerosene oil: a case report.

ABSTRACT:

Introduction

Kerosene is a freely accessible hydrocarbon used in Sri Lankan (and other Asian) households for cooking and for lighting lamps. Kerosene poisoning is rarely reported among adults and its toxicological effects are not well known. Metformin is a commonly used oral hypoglycemic drug and its overdose leads primarily to lactic acidosis. Combined poisoning of metformin and kerosene and their interactions have not been reported.

Case presentation

An 18-year-old, previously healthy, unmarried Sinhalese woman was referred following ingestion of 17.5 g of metformin and approximately 200 mL of kerosene oil in a suicide attempt. She had vomiting, burning epigastric pain, and a hypoglycemic seizure (capillary blood glucose of 42 mg/dL). Subsequently, she developed severe lac

SUBMITTER: Rathnapala A 

PROVIDER: S-EPMC3292833 | biostudies-literature | 2012 Jan

REPOSITORIES: biostudies-literature