UPDG: utilities package for data analysis of pooled DNA GWAS.

ABSTRACT:

Background

Despite being a well-established strategy for cost reduction in disease gene mapping, pooled DNA association study is much less popular than the individual DNA approach. This situation is especially true for pooled DNA genomewide association study (GWAS), for which very few computer resources have been developed for its data analysis. This motivates the development of UPDG (Utilities package for data analysis of Pooled DNA GWAS).

Results

UPDG represents a generalized framework for data analysis of pooled DNA GWAS with the integration of Unix/Linux shell operations, Perl programs and R scripts. With the input of raw intensity data from GWAS, UPDG performs the following tasks in a stepwise manner: raw data manipulation, correction for allelic preferential amplificat

SUBMITTER: Ho DW 

PROVIDER: S-EPMC3293712 | biostudies-literature | 2012 Jan

REPOSITORIES: biostudies-literature