Human Plasmodium knowlesi infection in Ranong province, southwestern border of Thailand.

ABSTRACT:

Background

Plasmodium knowlesi, a simian malaria parasite, has been reported in humans in many Southeast Asian countries. In Thailand, most of the limited numbers of cases reported so far were from areas near neighbouring countries, including Myanmar.

Methods

Blood samples collected from 171 Thai and 248 Myanmese patients attending a malaria clinic in Ranong province, Thailand, located near the Myanmar border were investigated for P. knowlesi using nested PCR assays. Positive samples were also investigated by PCR for Plasmodium falciparum, Plasmodium vivax, Plasmodium malariae and Plasmodium ovale, and were confirmed by sequencing the gene encoding the circumsporozoite protein (csp).

Results

Two samples, one obtained from a Thai and the other a Myanmese, were positive

SUBMITTER: Sermwittayawong N 

PROVIDER: S-EPMC3293766 | biostudies-literature | 2012 Feb

REPOSITORIES: biostudies-literature