Echocardiography, natriuretic peptides, and risk for incident heart failure in older adults: the Cardiovascular Health Study.

ABSTRACT:

Objectives

This study sought to examine the potential utility of echocardiography and N-terminal pro-B-type natriuretic peptide (NT-proBNP) for heart failure (HF) risk stratification in concert with a validated clinical HF risk score in older adults.

Background

Without clinical guidance, echocardiography and natriuretic peptides have suboptimal test characteristics for population-wide HF risk stratification. However, the value of these tests has not been examined in concert with a clinical HF risk score.

Methods

We evaluated the improvement in 5-year HF risk prediction offered by adding an echocardiographic score and/or NT-proBNP levels to the clinical Health Aging and Body Composition (ABC) HF risk score (base model) in 3,752 participants of the CHS (Cardiovascular H

SUBMITTER: Kalogeropoulos AP 

PROVIDER: S-EPMC3293933 | biostudies-literature | 2012 Feb

REPOSITORIES: biostudies-literature