Expressed sequence tag profiling identifies developmental and anatomic partitioning of gene expression in the mouse prostate.

ABSTRACT:

Background

The prostate gland is an organ with highly specialized functional attributes that serves to enhance the fertility of mammalian species. Much of the information pertaining to normal and pathological conditions affecting the prostate has been obtained through extensive developmental, biochemical and genetic analyses of rodent species. Although important insights can be obtained through detailed anatomical and histological assessments of mouse and rat models, further mechanistic explanations are greatly aided through studies of gene and protein expression.

Results

In this article we characterize the repertoire of genes expressed in the normal developing mouse prostate through the analysis of 50,562 expressed sequence tags derived from 14 mouse prostate cDNA libraries

SUBMITTER: Abbott DE 

PROVIDER: S-EPMC329418 | biostudies-literature | 2003

REPOSITORIES: biostudies-literature