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Emergence of oseltamivir-resistant pandemic (H1N1) 2009 virus within 48 hours.

ABSTRACT: An oseltamivir-resistant influenza A pandemic (H1N1) 2009 virus evolved and emerged from zero to 52% of detectable virus within 48 hours of a patient's exposure to oseltamivir. Phylogenetic analysis and data gathered by pyrosequencing and cloning directly on clinical samples suggest that the mutant emerged de novo.

SUBMITTER: Inoue M 

PROVIDER: S-EPMC3294403 | biostudies-literature |

REPOSITORIES: biostudies-literature

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